691Rifampin in the Treatment of Staphylococcal Prosthetic Joint Infections
نویسندگان
چکیده
Infections Shadi Parsaei, DO; Neeraja Ganeshraj, MPH; Alice P. Gu, MPH; Qian Liu, MPH; Carey-Ann D. Burnham, PhD; David K. Warren, MD, MPH, FIDSA, FSHEA; Michael A. Lane, MD, MSc; Division of Infectious Diseases, Department of Medicine, Washington University School of Medicine, St. Louis, MO; Pediatrics, Pathology and Immunology, Washington University School of Medicine, St Louis, MO; Washington University School of Medicine, St. Louis, MO
منابع مشابه
Treatment of Staphylococcal Joint Infection in the Rabbit by Administration of Systemic Antibiotics and Intra-articular Corticosteroids
Background/objective: Despite the present routine treatment of septic arthritis with antibacterial agents, articular damage is persistent and frequently leads to loss of joint function. The aim of this study was to assess the effect of intra-articular corticosteroids added to systemic antibiotics in the treatment of experimental staphylococcal knee joint infection in rabbits. Methods: Thirty r...
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UNLABELLED Small colony variants (SCVs) are naturally occurring subpopulations of bacteria. The clinical characteristics and treatment outcomes of patients with prosthetic joint infection (PJI) caused by staphylococcal SCVs are unknown. This study was a retrospective series of 113 patients with staphylococcal PJI, with prospective testing of archived sonicate fluid samples. SCVs were defined us...
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BACKGROUND AND PURPOSE Prosthetic joint infection (PJI) is a leading cause of early revision after total knee arthroplasty (TKA). Open debridement with exchange of tibial insert allows treatment of infection with retention of fixed components. We investigated the success rate of this procedure in the treatment of knee PJIs in a nationwide material, and determined whether the results were affect...
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BACKGROUND We report the outcome of debridement and prosthesis retention plus long-term levofloxacin/rifampicin treatment of prosthetic joint infections. METHODS Staphylococcal prosthesis joint infections were defined by positive culture of joint aspirate, intraoperative debridement specimens, or sinus tract discharge in the presence of clinical criteria. Patients received long-term oral levo...
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